Coughbutton, my podcaster’s iPhone-based cough button for your Mac, has been upgraded to 1.3 and undergone a major switcharoo. It now works with Skype (and, by default, only with Skype), which is all I really needed anyway.
I found (during the podcast I recorded last night) that with the separate channel that Skype uses, MuteMyMic was failing on some USB microphones within Skype. Directly muting Skype also has the benefit that I can send ON/OFF commands instead of just toggling and hoping everything stays in sync.
More reliable, more practical and made with real sugar.
Coughbutton 1.3 on Github.